Anti-ARHGEF18 Antibody

Rs. 68,577.00
SKU stj70465

General Information

Product name Anti-ARHGEF18 Antibody
Short Description Goat polyclonal to ARHGEF18
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-ARHGEF18 Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 151.6 kDa
Database Links
Alternative Names ARHGEF18Rho guanine nucleotide exchange factor 18 antibody114 kDa Rho-specific guanine nucleotide exchange factor antibodyp114-Rho-GEF antibodyp114RhoGEF antibodySeptin-associated RhoGEF antibodySA-RhoGEFARHGEF18 antibodyKIAA0521
Function Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases, Its activation induces formation of actin stress fibers, Also acts as a GEF for RAC1, inducing production of reactive oxygen species (ROS), Does not act as a GEF for CDC42, The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production, Required for EPB41L4B-mediated regulation of the circumferential actomyosin belt in epithelial cells ,
Cellular Localization Cytoplasm,
Tissue Specificity Expressed in all tissues tested with highest expression in kidney and pancreas, weakly or not expressed in liver, skeletal muscle and testis, expressed in eosinophils ,
Swiss-Prot Key

 

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