Anti-ARNT Antibody

Rs. 68,577.00
SKU stj73329

General Information

Product name Anti-ARNT Antibody
Short Description Goat polyclonal to ARNT
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-ARNT Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 86.6 kDa
Database Links
Alternative Names ARNTAryl hydrocarbon receptor nuclear translocator antibodyARNT protein antibodyClass E basic helix-loop-helix protein 2 antibodybHLHe2 antibodyDioxin receptor antibodynuclear translocator antibodyHypoxia-inducible factor 1-beta antibodyHIF-1-beta antibodyHIF1-betaARNT antibodyBHLHE2
Function Required for activity of the Ah (dioxin) receptor, This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding, The complex then initiates transcription of genes involved in the activation of PAH procarcinogens, The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity), The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription ,
Cellular Localization Nucleus
Tissue Specificity
Swiss-Prot Key

 

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