Anti-ASAH1 Antibody

Rs. 45,619.00
SKU stj28610

General Information

Product name Anti-ASAH1 Antibody
Short Description Rabbit polyclonal to ASAH1
Description This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-ASAH1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 140-389 of human ASAH1 (NP_001120977.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 44.7 kDa
Database Links
Alternative Names ASAH1Acid ceramidase antibodyAC antibodyACDase antibodyAcid CDaseASAH1 antibodyASAH antibodyHSD-33 antibodyHSD33
Function Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
Cellular Localization Lysosome
Tissue Specificity Broadly expressed with highest expression in heart
Swiss-Prot Key

 

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