Anti-ASC-1 antibody

Rs. 50,211.00
SKU stj91731

General Information

Product name Anti-ASC-1 antibody
Short Description
Description Rabbit polyclonal to ASC-1.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-ASC-1 antibody
Immunogen Synthesized peptide derived from human ASC-1
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 66 kDa
Database Links
Alternative Names Activating signal cointegrator 1 antibody
Thyroid receptor-interacting protein 4 antibody
TR-interacting protein 4 antibody
TRIP-4 antibody
Function Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation . Also involved in androgen receptor transactivation . Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B . May play a role in the development of neuromuscular junction . May play a role in late myogenic differentiation .
Cellular Localization Nucleus Cytoplasm, cytosol Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic under conditions of serum deprivation . Colocalizes with NEK6 in the centrosome .
Tissue Specificity
Swiss-Prot Key

 

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