Anti-ASTL Antibody

Rs. 45,619.00
SKU stj117183

General Information

Product name Anti-ASTL Antibody
Short Description Rabbit polyclonal to ASTL
Description
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Astacin-like metalloendopeptidase
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 24-431 of human ASTL (NP_001002036.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 45.9 kDa
Database Links
Alternative Names ASTLAstacin-like metalloendopeptidase ASTL
Function Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization, Plays a role in the polyspermy inhibition, Probably acts as a protease for the post-fertilization cleavage of ZP2, Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity).
Cellular Localization Cytoplasm.
Tissue Specificity Expressed in promyelocytic leukemia hl-60 cells, burkitt's lymphoma raji cells, and also in some ovarian carcinomas, not detected in normal tissues.
Swiss-Prot Key

 

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