Anti-AsymmetricH4R3me2a-(DiMethyl) Antibody

Rs. 50,211.00
SKU stj23973

General Information

Product name Anti-AsymmetricH4R3me2a-(DiMethyl) Antibody
Short Description Rabbit Polyclonal to AsymmetricH4R3me2a(DiMethyl)
Description Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Applications WB,IHC,IF,IP
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:100
Protein Name Anti-AsymmetricH4R3me2a-(DiMethyl) Antibody
Immunogen A synthetic methylated peptide corresponding to residues surrounding Arg3 of human histone H4
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 11.4 kDa
Database Links
Alternative Names HIST1H4AHistone H4HIST1H4A antibodyH4/A antibodyH4FA; antibodyHIST1H4B antibodyH4/I antibodyH4FI; antibodyHIST1H4C antibodyH4/G antibodyH4FG; antibodyHIST1H4D antibodyH4/B antibodyH4FB; antibodyHIST1H4E antibodyH4/J antibodyH4FJ; antibodyHIST1H4F antibodyH4/C antibodyH4FC; antibodyHIST1H4H antibodyH4/H antibodyH4FH; antibodyHIST1H4I antibodyH4/M antibodyH4FM; antibodyHIST1H4J antibodyH4/E antibodyH4FE; antibodyHIST1H4K antibodyH4/D antibodyH4FD; antibodyHIST1H4L antibodyH4/K antibodyH4FK; antibodyHIST2H4A antibodyH4/N antibodyH4F2 antibodyH4FN antibodyHIST2H4; antibodyHIST2H4B antibodyH4/O antibodyH4FO; antibodyHIST4H4
Function Core component of nucleosome, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Cellular Localization Nucleus, Chromosome
Tissue Specificity
Swiss-Prot Key

 

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