Anti-ASZ1 Antibody

Rs. 45,619.00
SKU stj116657

General Information

Product name Anti-ASZ1 Antibody
Short Description Rabbit polyclonal to ASZ1
Description
Applications WB
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
Protein Name Ankyrin repeatSAM and basic leucine zipper domain-containing protein 1Ankyrin-like protein 1Germ cell-specific ankyrinSAM and basic leucine zipper domain-containing protein
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human ASZ1 (NP_570124.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 53.5 kDa
Database Links
Alternative Names ASZ1Ankyrin repeat antibodySAM and basic leucine zipper domain-containing protein 1 antibodyAnkyrin-like protein 1 antibodyGerm cell-specific ankyrin antibodySAM and basic leucine zipper domain-containing proteinASZ1 antibodyALP1 antibodyANKL1 antibodyC7orf7 antibodyGASZ
Function Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity, Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process, Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons, May act by mediating protein-protein interactions during germ cell maturation (By similarity).
Cellular Localization Cytoplasm.
Tissue Specificity Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary.
Swiss-Prot Key

 

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