Anti-Atg4b antibody

Rs. 50,211.00
SKU stj91759

General Information

Product name Anti-Atg4b antibody
Short Description
Description Rabbit polyclonal to Atg4b.
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000
Protein Name Anti-Atg4b antibody
Immunogen Synthesized peptide derived from human Atg4b
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 44 kDa
Database Links
Alternative Names Cysteine protease ATG4B antibody
AUT-like 1 cysteine endopeptidase antibody
Autophagin-1 antibody
Autophagy-related cysteine endopeptidase 1 antibody
Autophagy-related protein 4 homolog B antibody
hAPG4B antibody
APG4B antibody
AUTL1 antibody
KIAA0943 antibody
Function Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Cellular Localization Cytoplasm
Tissue Specificity Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
Swiss-Prot Key

 

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