Anti-ATG4C Antibody

Rs. 68,577.00
SKU stj71866

General Information

Product name Anti-ATG4C Antibody
Short Description Goat polyclonal to ATG4C
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-ATG4C Antibody
Immunogen C- terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 52.5 kDa
Database Links
Alternative Names ATG4CCysteine protease ATG4C ATG4C antibodyAPG4C antibodyAUTL1 antibodyAUTL3
Function Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy, Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity), Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine, Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy, Has also an activity of delipidating enzyme for the PE-conjugated forms,
Cellular Localization Cytoplasm
Tissue Specificity Highly expressed in skeletal muscle, heart, liver and testis,
Swiss-Prot Key

 

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