Anti-ATP1A2 Antibody

Rs. 45,619.00
SKU stj115748

General Information

Product name Anti-ATP1A2 Antibody
Short Description Rabbit polyclonal to ATP1A2
Description The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Sodium/potassium-transporting ATPase subunit alpha-2Na(+/K(+ATPase alpha-2 subunit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ATP1A2 (NP_000693.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 112.3 kDa
Database Links
Alternative Names ATP1A2Sodium/potassium-transporting ATPase subunit alpha-2 antibodyNa(+ antibody/K(+ antibodyATPase alpha-2 subunitATP1A2 antibodyKIAA0778
Function This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane, This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients
Cellular Localization Membrane
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed