Anti-ATP5C1 Antibody

Rs. 45,619.00
SKU stj117452

General Information

Product name Anti-ATP5C1 Antibody
Short Description Rabbit polyclonal to ATP5F1C
Description This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14.
Applications WB
Dilution range WB 1:200 - 1:2000
Protein Name ATP synthase subunit gammamitochondrialATP synthase F1 subunit gammaF-ATPase gamma subunit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 26-298 of human ATP5C1 (NP_001001973.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 33 kDa
Database Links
Alternative Names ATP5F1CATP synthase subunit gamma antibodymitochondrial antibodyATP synthase F1 subunit gamma antibodyF-ATPase gamma subunitATP5F1C antibodyATP5C antibodyATP5C1 antibodyATP5CL1
Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain, F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk, During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation, Part of the complex F(1) domain and the central stalk which is part of the complex rotary element, The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3), Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Cellular Localization Mitochondrion inner membrane
Tissue Specificity Isoform heart is expressed specifically in the heart and skeletal muscle, which require rapid energy supply, isoform liver is expressed in the brain, liver and kidney, isoform heart and isoform liver are expressed in the skin, intestine, stomach and aorta
Swiss-Prot Key

 

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