Anti-ATP6AP2 Antibody

Rs. 45,619.00
SKU stj28614

General Information

Product name Anti-ATP6AP2 Antibody
Short Description Rabbit polyclonal to ATP6AP2
Description This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-ATP6AP2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 251-350 of human ATP6AP2 (NP_005756.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 39 kDa
Database Links
Alternative Names ATP6AP2Renin receptor antibodyATPase H(+ antibody-transporting lysosomal accessory protein 2 antibodyATPase H(+ antibody-transporting lysosomal-interacting protein 2 antibodyER-localized type I transmembrane adaptor antibodyEmbryonic liver differentiation factor 10 antibodyN14F antibodyRenin/prorenin receptor antibodyVacuolar ATP synthase membrane sector-associated protein M8-9 antibodyATP6M8-9 antibodyV-ATPase M8.9 subunitATP6AP2 antibodyATP6IP2 antibodyCAPER antibodyELDF10 antibodyHT028 antibodyMSTP009 antibodyPSEC0072
Function Functions as a renin and prorenin cellular receptor, May mediate renin-dependent cellular responses by activating ERK1 and ERK2, By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).
Cellular Localization Membrane
Tissue Specificity Expressed in brain, heart, placenta, liver, kidney and pancreas, barely detectable in lung and skeletal muscles, in the kidney cortex it is restricted to the mesangium of glomeruli, in the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with ren, expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.
Swiss-Prot Key

 

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