Anti-ATP6V1B2 Antibody

Rs. 45,619.00
SKU stj22729

General Information

Product name Anti-ATP6V1B2 Antibody
Short Description Rabbit polyclonal to ATP6V1B2
Description This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-ATP6V1B2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 262-511 of human ATP6V1B2 (NP_001684.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 56.5 kDa
Database Links
Alternative Names ATP6V1B2V-type proton ATPase subunit B antibodybrain isoform antibodyV-ATPase subunit B 2 antibodyEndomembrane proton pump 58 kDa subunit antibodyHO57 antibodyVacuolar proton pump subunit B 2ATP6V1B2 antibodyATP6B2 antibodyVPP3
Function Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase, V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells
Cellular Localization Endomembrane system
Tissue Specificity
Swiss-Prot Key

 

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