Anti-ATRIP Antibody

Rs. 45,619.00
SKU stj116274

General Information

Product name Anti-ATRIP Antibody
Short Description Rabbit polyclonal to ATRIP
Description This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications WB,IF,IP
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
IP 1:20 - 1:50
Protein Name ATR-interacting proteinATM and Rad3-related-interacting protein
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ATRIP (NP_569055.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 85.8 kDa
Database Links
Alternative Names ATRIPATR-interacting protein antibodyATM and Rad3-related-interacting proteinATRIP antibodyAGS1
Function Required for checkpoint signaling after DNA damage, Required for ATR expression, possibly by stabilizing the protein.
Cellular Localization Nucleus.
Tissue Specificity Ubiquitous.
Swiss-Prot Key

 

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