Anti-ATXN3 Antibody

Rs. 45,619.00
SKU stj114961

General Information

Product name Anti-ATXN3 Antibody
Short Description Rabbit polyclonal to ATXN3
Description Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Ataxin-3
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human ATXN3 (NP_004984.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 41.2 kDa
Database Links
Alternative Names ATXN3Ataxin-3 ATXN3 antibodyATX3 antibodyMJD antibodyMJD1 antibodySCA3
Function Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates.
Cellular Localization Nucleus matrix.
Tissue Specificity Ubiquitous
Swiss-Prot Key

 

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