Anti-B4GALT7 Antibody

Rs. 61,689.00
SKU stj26698

General Information

Product name Anti-B4GALT7 Antibody
Short Description Rabbit polyclonal to B4GALT7
Description This gene is a member of the beta-1,4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. Mutations in this gene have been associated with the progeroid form of Ehlers-Danlos syndrome.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-B4GALT7 Antibody
Immunogen A synthetic Peptide of human B4GALT7
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 37.4 kDa
Database Links
Alternative Names B4GALT7Beta-1,4-galactosyltransferase 7 antibodyBeta-1,4-GalTase 7 antibodyBeta4Gal-T7 antibodyb4Gal-T7 antibody]B4GALT7 antibodyXGALT1 antibodyUNQ748/PRO1478
Function Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts.
Cellular Localization Golgi apparatus, Golgi stack membrane
Tissue Specificity High expression in heart, pancreas and liver, medium in placenta and kidney, low in brain, skeletal muscle and lung
Swiss-Prot Key

 

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