Anti-BAIAP2L1 Antibody

Rs. 45,619.00
SKU stj117367

General Information

Product name Anti-BAIAP2L1 Antibody
Short Description Rabbit polyclonal to BAIAP2L1
Description This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
Applications IF
Dilution range IF 1:50 - 1:200
Protein Name Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1BAI1-associated protein 2-like protein 1Insulin receptor tyrosine kinase substrate
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human BAIAP2L1 (NP_061330.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 56.9 kDa
Database Links
Alternative Names BAIAP2L1Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 antibodyBAI1-associated protein 2-like protein 1 antibodyInsulin receptor tyrosine kinase substrateBAIAP2L1 antibodyIRTKS
Function May function as adapter protein, Involved in the formation of clusters of actin bundles, Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.
Cellular Localization Cytoplasm, cytoskeleton.
Tissue Specificity
Swiss-Prot Key

 

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