Anti-BANP Antibody

Rs. 61,689.00
SKU stj22760

General Information

Product name Anti-BANP Antibody
Short Description Rabbit polyclonal to BANP
Description This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-BANP Antibody
Immunogen A synthetic peptide of human BANP
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 56.5 kDa
Database Links
Alternative Names BANPProtein BANP antibodyBEN domain-containing protein 1 antibodyBtg3-associated nuclear protein antibodyScaffold/matrix-associated region-1-binding proteinBANP antibodyBEND1 antibodySMAR1
Function Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function, Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer, Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels, Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).
Cellular Localization Nucleus
Tissue Specificity Down-regulated in breast cancer cell lines.
Swiss-Prot Key

 

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