Anti-BCAP31 Antibody

Rs. 45,619.00
SKU stj29136

General Information

Product name Anti-BCAP31 Antibody
Short Description Rabbit polyclonal to BCAP31
Description This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16.
Applications WB,IF,IP
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
IP 1:50 - 1:100
Protein Name Anti-BCAP31 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 127-246 of human BCAP31 (NP_001243376.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 28 kDa
Database Links
Alternative Names BCAP31B-cell receptor-associated protein 31 antibodyBCR-associated protein 31 antibodyBap31 antibody6C6-AG tumor-associated antigen antibodyProtein CDM antibodyp28BCAP31 antibodyBAP31 antibodyDXS1357E
Function Functions as a chaperone protein, Is one of the most abundant endoplasmic reticulum (ER) proteins, Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD), Also serves as a cargo receptor for the export of transmembrane proteins, May be involved in CASP8-mediated apoptosis.
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity Ubiquitous, highly expressed in neurons and discrete endocrine cells.
Swiss-Prot Key

 

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