General Information
| Product name | Anti-BCO2 Antibody |
|---|---|
| Short Description | Rabbit polyclonal to BCO2 |
| Description | This gene encodes an enzyme which oxidizes carotenoids such as beta-carotene during the biosynthesis of vitamin A. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Applications | WB |
| Dilution range | WB 1:500 - 1:2000 |
| Protein Name | Anti-BCO2 Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 170-410 of human BCO2 (NP_001243327.1). |
| Storage Instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Type of Usage | For Research Use Only (RUO). |
Product Properties
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Reactivity | |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Isotype | IgG |
| Formulation | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Target
| Gene ID | |
|---|---|
| Gene Symbol | |
| Molecular Weight | 65.7 kDa |
| Database Links | |
| Alternative Names | BCO2Beta,beta-carotene 9',10'-oxygenase BCO2 antibodyBCDO2 |
| Function | Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone, Besides beta-carotene, lycopene is also oxidatively cleaved, The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects. |
| Cellular Localization | Mitochondrion |
| Tissue Specificity | Highly expressed in retinal pigment epithelium, also expressed in stomach, small intestine, liver, testis, kidney, adrenal gland, pancreas, heart, skeletal muscle and prostate (at protein level). |
| Swiss-Prot Key |