Anti-BCOR Antibody

Rs. 45,619.00
SKU stj22784

General Information

Product name Anti-BCOR Antibody
Short Description Rabbit polyclonal to BCOR
Description The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-BCOR Antibody
Immunogen Recombinant protein of human BCOR
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 192.2 kDa
Database Links
Alternative Names BCORBCL-6 corepressor antibodyBCoRBCOR antibodyKIAA1575
Function Transcriptional corepressor, May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3, This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor, Involved in the repression of TFAP2A
Cellular Localization Nucleus
Tissue Specificity Ubiquitously expressed.
Swiss-Prot Key

 

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