Anti-BDNF Antibody

Rs. 50,211.00
SKU stj113473

General Information

Product name Anti-BDNF Antibody
Short Description Rabbit polyclonal to BDNF
Description This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Protein Name Brain-derived neurotrophic factorBDNFAbrineurin
Immunogen Recombinant protein of human BDNF
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 27.8 kDa
Database Links
Alternative Names BDNFBrain-derived neurotrophic factor antibodyBDNF antibodyAbrineurinBDNF
Function During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems, Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology, Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS, The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Cellular Localization Secreted
Tissue Specificity Brain, highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum, also expressed in heart, lung, skeletal muscle, testis, prostate and placenta.
Swiss-Prot Key

 

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