Anti-BIRC6 Antibody

Rs. 68,577.00
SKU stj70295

General Information

Product name Anti-BIRC6 Antibody
Short Description Goat polyclonal to BIRC6
Description
Applications ELISA, IHC
Dilution range
Protein Name Anti-BIRC6 Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 530.3 kDa
Database Links
Alternative Names BIRC6Baculoviral IAP repeat-containing protein 6 BIRC6 antibodyKIAA1289
Function Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase, Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase, Its tragets include CASP9 and DIABLO/SMAC, Acts as an inhibitor of CASP3, CASP7 and CASP9, Important regulator for the final stages of cytokinesis, Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification,
Cellular Localization Golgi apparatus, trans-Golgi network membrane,
Tissue Specificity Expressed in brain cancer cells
Swiss-Prot Key

 

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