Anti-BMP10 Antibody

Rs. 45,619.00
SKU stj117205

General Information

Product name Anti-BMP10 Antibody
Short Description Rabbit polyclonal to BMP10
Description The protein encoded by this gene is a member of the TGF-beta family of growth factors. Data suggest that the similar protein in mouse plays an important role in trabeculation of the embryonic heart. In human, this protein may signal through receptor serine/threonine kinases.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Bone morphogenetic protein 10BMP-10
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 22-316 of human BMP10 (NP_055297.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 48 kDa
Database Links
Alternative Names BMP10Bone morphogenetic protein 10 antibodyBMP-10BMP10
Function Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5, Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors, Inhibits endothelial cell migration and growth, May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Cellular Localization Secreted
Tissue Specificity Detected in mammary epithelia (at protein level).
Swiss-Prot Key

 

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