Anti-BMP4 Antibody

Rs. 50,211.00
SKU stj113465

General Information

Product name Anti-BMP4 Antibody
Short Description Rabbit polyclonal to BMP4
Description This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
Protein Name Bone morphogenetic protein 4BMP-4Bone morphogenetic protein 2BBMP-2B
Immunogen Recombinant protein of human BMP4
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 46.6 kDa
Database Links
Alternative Names BMP4Bone morphogenetic protein 4 antibodyBMP-4 antibodyBone morphogenetic protein 2B antibodyBMP-2BBMP4 antibodyBMP2B antibodyDVR4
Function Induces cartilage and bone formation, Also act in mesoderm induction, tooth development, limb formation and fracture repair, Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).
Cellular Localization Secreted, extracellular space, extracellular matrix
Tissue Specificity Expressed in the lung and lower levels seen in the kidney, present also in normal and neoplastic prostate tissues, and prostate cancer cell lines
Swiss-Prot Key

 

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