Anti-BMP7 Antibody

Rs. 61,689.00
SKU stj22817

General Information

Product name Anti-BMP7 Antibody
Short Description Rabbit polyclonal to BMP7
Description This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:20 - 1:50
Protein Name Anti-BMP7 Antibody
Immunogen A synthetic peptide of human BMP7
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 49.3 kDa
Database Links
Alternative Names BMP7Bone morphogenetic protein 7 antibodyBMP-7 antibodyOsteogenic protein 1 antibodyOP-1 antibodyEptotermin alfaBMP7 antibodyOP1
Function Induces cartilage and bone formation, May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis, Plays a role in calcium regulation and bone homeostasis
Cellular Localization Secreted
Tissue Specificity Expressed in the kidney and bladder, lower levels seen in the brain
Swiss-Prot Key

 

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