Anti-BPIFA1 Antibody

Rs. 68,577.00
SKU stj72784

General Information

Product name Anti-BPIFA1 Antibody
Short Description Goat polyclonal to BPIFA1
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-BPIFA1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 26.7 kDa
Database Links
Alternative Names BPIFA1BPI fold-containing family A member 1 antibodyLung-specific protein X antibodyNasopharyngeal carcinoma-related protein antibodyPalate lung and nasal epithelium clone protein antibodySecretory protein in upper respiratory tracts antibodyShort PLUNC1 antibodySPLUNC1 antibodyTracheal epithelium-enriched protein antibodyVon Ebner protein HlBPIFA1 antibodyLUNX antibodyNASG antibodyPLUNC antibodySPLUNC1 antibodySPURT antibodyUNQ787/PRO1606
Function Plays a role in the innate immune responses of the upper airways, Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P,aeruginosa and K,pneumoniae, Binds bacterial lipopolysaccharide (LPS), Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus, Plays a role in the airway inflammatory response after exposure to irritants, May attract macrophages and neutrophils, May be associated with tumor progression,
Cellular Localization Secreted,
Tissue Specificity Lung, upper airways and nasopharyngeal regions, including trachea and nasal epithelium, specifically expressed in the secretory ducts and submucosal glands of tracheobronchial tissues, highest expression in the trachea and progressive decrease from proximal (bronchial) to distal (bronchiolar) airways, also expressed in lung cancers and some other types of cancer,
Swiss-Prot Key

 

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