Anti-BRAF Antibody

Rs. 50,211.00
SKU stj22827

General Information

Product name Anti-BRAF Antibody
Short Description Mouse monoclonal to BRAF
Description This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-BRAF Antibody
Immunogen Recombinant protein of human BRAF
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Mouse
Clonality Monoclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 84.4 kDa
Database Links
Alternative Names BRAFSerine/threonine-protein kinase B-raf BRAF antibodyBRAF1 antibodyRAFB1
Function Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus, May play a role in the postsynaptic responses of hippocampal neuron, Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.
Cellular Localization Nucleus
Tissue Specificity Brain and testis
Swiss-Prot Key

 

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