Anti-BRD2 Antibody

Rs. 61,689.00
SKU stj29878

General Information

Product name Anti-BRD2 Antibody
Short Description Rabbit polyclonal to BRD2
Description This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:1000
IHC 1:50 - 1:100
Protein Name Anti-BRD2 Antibody
Immunogen A synthetic peptide of human BRD2
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 88.1 kDa
Database Links
Alternative Names BRD2Bromodomain-containing protein 2 antibodyO27.1.1 antibodyReally interesting new gene 3 proteinBRD2 antibodyKIAA9001 antibodyRING3
Function May play a role in spermatogenesis or folliculogenesis (By similarity), Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling, Regulates transcription of the CCND1 gene, Plays a role in nucleosome assembly.
Cellular Localization Nucleus.
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed