Anti-BRWD1 Antibody

Rs. 45,619.00
SKU stj114530

General Information

Product name Anti-BRWD1 Antibody
Short Description Rabbit polyclonal to BRWD1
Description This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.
Applications WB
Dilution range WB 1:1000 - 1:3000
Protein Name Bromodomain and WD repeat-containing protein 1WD repeat-containing protein 9
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human BRWD1 (NP_001007247.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 262.9 kDa
Database Links
Alternative Names BRWD1Bromodomain and WD repeat-containing protein 1 antibodyWD repeat-containing protein 9BRWD1 antibodyC21orf107 antibodyWDR9
Function May be a transcriptional activator, May be involved in chromatin remodeling (By similarity), Plays a role in the regulation of cell morphology and cytoskeletal organization, Required in the control of cell shape.
Cellular Localization Cytoplasm, Nucleus
Tissue Specificity Ubiquitously expressed.
Swiss-Prot Key

 

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