Anti-C1QC Antibody

Rs. 45,619.00
SKU stj117864

General Information

Product name Anti-C1QC Antibody
Short Description Rabbit polyclonal to C1QC
Description This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
Protein Name Complement C1q subcomponent subunit C
Immunogen A synthetic peptide corresponding to a sequence within amino acids 50-150 of human C1QC (NP_001107573.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 25.8 kDa
Database Links
Alternative Names C1QCComplement C1q subcomponent subunit CC1QC antibodyC1QG
Function C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system, The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes
Cellular Localization Secreted
Tissue Specificity
Swiss-Prot Key

 

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