Anti-C3a Antibody

Rs. 45,619.00
SKU stj28959

General Information

Product name Anti-C3a Antibody
Short Description Rabbit polyclonal to C3
Description Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Protein Name Anti-C3a Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1364-1663 of human C3 (NP_000055.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 187.1 kDa
Database Links
Alternative Names C3Complement C3 antibodyC3 and PZP-like alpha-2-macroglobulin domain-containing protein 1C3 antibodyCPAMD1
Function C3 plays a central role in the activation of the complement system, Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways, After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates
Cellular Localization Secreted
Tissue Specificity Plasma, the acylation stimulating protein (asp) is expressed in adipocytes and released into the plasma during both the fasting and postprandial periods.
Swiss-Prot Key

 

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