Anti-C3G antibody

Rs. 50,211.00
SKU stj91934

General Information

Product name Anti-C3G antibody
Short Description
Description Rabbit polyclonal to C3G.
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:5000
Protein Name Anti-C3G antibody
Immunogen Synthesized peptide derived from human C3G around the non-phosphorylation site of Y504.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 120 kDa
Database Links
Alternative Names Rap guanine nucleotide exchange factor 1 antibody
CRK SH3-binding GNRP antibody
Guanine nucleotide-releasing factor 2 antibody
Protein RAPGEF1 antibody
GRF2 antibody
Function Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.
Cellular Localization Early endosome
Tissue Specificity Ubiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver.
Swiss-Prot Key

 

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