Anti-CA8 Antibody

Rs. 45,619.00
SKU stj29682

General Information

Product name Anti-CA8 Antibody
Short Description Rabbit polyclonal to CA8
Description The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CA8 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human CA8 (NP_004047.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 33 kDa
Database Links
Alternative Names CA8Carbonic anhydrase-related protein antibodyCARP antibodyCarbonic anhydrase VIII antibodyCA-VIIICA8 antibodyCALS
Function Does not have a carbonic anhydrase catalytic activity
Cellular Localization
Tissue Specificity
Swiss-Prot Key

 

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