Anti-CACNA1G Antibody

Rs. 57,098.00
SKU stj72033

General Information

Product name Anti-CACNA1G Antibody
Short Description Goat polyclonal to CACNA1G
Description
Applications ELISA
Dilution range
Protein Name Anti-CACNA1G Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 262.5 kDa
Database Links
Alternative Names CACNA1GVoltage-dependent T-type calcium channel subunit alpha-1G antibodyCav3.1c antibodyNBR13 antibodyVoltage-gated calcium channel subunit alpha Cav3.1CACNA1G antibodyKIAA1123
Function Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death, The isoform alpha-1G gives rise to T-type calcium currents, T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil, A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation, T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle, They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes,
Cellular Localization Cell membrane
Tissue Specificity Highly expressed in brain, in particular in the amygdala, subthalamic nuclei, cerebellum and thalamus, moderate expression in heart
Swiss-Prot Key

 

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