Anti-CADM1 Antibody

Rs. 68,577.00
SKU stj72327

General Information

Product name Anti-CADM1 Antibody
Short Description Goat polyclonal to CADM1
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-CADM1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 48.5 kDa
Database Links
Alternative Names CADM1Cell adhesion molecule 1 antibodyImmunoglobulin superfamily member 4 antibodyIgSF4 antibodyNectin-like protein 2 antibodyNECL-2 antibodySpermatogenic immunoglobulin superfamily antibodySgIgSF antibodySynaptic cell adhesion molecule antibodySynCAM antibodyTumor suppressor in lung cancer 1 antibodyTSLC-1CADM1 antibodyIGSF4 antibodyIGSF4A antibodyNECL2 antibodySYNCAM antibodyTSLC1
Function Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner, Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner, Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells, Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo, May contribute to the less invasive phenotypes of lepidic growth tumor cells, In mast cells, may mediate attachment to and promote communication with nerves, CADM1, together with MITF, is essential for development and survival of mast cells in vivo, Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity), May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons, May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa,
Cellular Localization Cell membrane
Tissue Specificity
Swiss-Prot Key

 

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