Anti-CAMK2A Antibody

Rs. 61,689.00
SKU stj22870

General Information

Product name Anti-CAMK2A Antibody
Short Description Rabbit polyclonal to CAMK2A
Description The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Applications WB,IHC
Dilution range WB 1:200 - 1:1000
IHC 1:20 - 1:200
Protein Name Anti-CAMK2A Antibody
Immunogen A synthetic peptide of human CAMK2A
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 54.1 kDa
Database Links
Alternative Names CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha antibodyCaM kinase II subunit alpha antibodyCaMK-II subunit alphaCAMK2A antibodyCAMKA antibodyKIAA0968
Function Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation, Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity), Regulates dendritic spine development.
Cellular Localization Cell junction, synapse
Tissue Specificity
Swiss-Prot Key

 

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