Anti-CAMLG Antibody

Rs. 45,619.00
SKU stj115674

General Information

Product name Anti-CAMLG Antibody
Short Description Rabbit polyclonal to CAMLG
Description The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Applications WB
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
Protein Name Calcium signal-modulating cyclophilin ligandCAML
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CAMLG (NP_001736.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 33 kDa
Database Links
Alternative Names CAMLGCalcium signal-modulating cyclophilin ligand antibodyCAMLCAMLG antibodyCAML
Function Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction, Binds to cyclophilin B
Cellular Localization Membrane
Tissue Specificity Ubiquitous, highest levels in brain, testis and ovary
Swiss-Prot Key

 

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