Anti-CAPNS1 Antibody

Rs. 45,619.00
SKU stj28622

General Information

Product name Anti-CAPNS1 Antibody
Short Description Rabbit polyclonal to CAPNS1
Description This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-CAPNS1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 69-268 of human CAPNS1 (NP_001740.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 28.3 kDa
Database Links
Alternative Names CAPNS1Calpain small subunit 1 antibodyCSS1 antibodyCalcium-activated neutral proteinase small subunit antibodyCANP small subunit antibodyCalcium-dependent protease small subunit antibodyCDPS antibodyCalcium-dependent protease small subunit 1 antibodyCalpain regulatory subunitCAPNS1 antibodyCAPN4 antibodyCAPNS
Function Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed