Anti-CARD 11 antibody

Rs. 50,211.00
SKU stj92000

General Information

Product name Anti-CARD 11 antibody
Short Description
Description Rabbit polyclonal to CARD 11.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000
Protein Name Anti-CARD 11 antibody
Immunogen Synthesized peptide derived from human CARD 11
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 130 kDa
Database Links
Alternative Names Caspase recruitment domain-containing protein 11 antibody
CARD-containing MAGUK protein 1 antibody
Carma 1 antibody
CARMA1 antibody
Function Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
Cellular Localization Cytoplasm Membrane raft. Colocalized with DPP4 in membrane rafts.
Tissue Specificity Detected in adult peripheral blood leukocytes, thymus, spleen and liver. Also found in promyelocytic leukemia HL-60 cells, chronic myelogenous leukemia K-562 cells, Burkitt's lymphoma Raji cells and colorectal adenocarcinoma SW480 cells. Not detected in HeLaS3, MOLT-4, A-549 and G431 cells.
Swiss-Prot Key

 

You recently viewed

Clear recently viewed