Anti-CARD16 Antibody

Rs. 57,098.00
SKU stj70095

General Information

Product name Anti-CARD16 Antibody
Short Description Goat polyclonal to CARD16
Description
Applications ELISA, IF, FC
Dilution range
Protein Name Anti-CARD16 Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 22.6 kDa
Database Links
Alternative Names CARD16Caspase recruitment domain-containing protein 16 antibodyCaspase recruitment domain-only protein 1 antibodyCARD-only protein 1 antibodyCaspase-1 inhibitor COP antibodyPseudo interleukin-1 beta converting enzyme antibodyPseudo-ICE antibodyPseudo-IL1B-converting enzymeCARD16 antibodyCOP antibodyCOP1
Function Caspase inhibitor, Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation, Inhibits the release of IL1B in response to LPS in monocytes, Also induces NF-kappa-B activation during the pro-inflammatory cytokine response, Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death, Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2,
Cellular Localization
Tissue Specificity Widely expressed, expressed at higher level in placenta, spleen, lymph node and bone marrow, weakly or not expressed in thymus,
Swiss-Prot Key

 

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