Anti-Casein Kinase Iα antibody

Rs. 50,211.00
SKU stj92011

General Information

Product name Anti-Casein Kinase Iα antibody
Short Description
Description Rabbit polyclonal to Casein Kinase Iα.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000
Protein Name Anti-Casein Kinase Iα antibody
Immunogen Synthesized peptide derived from human Casein Kinase Iα around the non-phosphorylation site of Y321.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 35 kDa
Database Links
Alternative Names Casein kinase I isoform alpha antibody
CKI-alpha antibody
CK1 antibody
Function Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis . May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration .
Cellular Localization Cytoplasm Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Chromosome, centromere, kinetochore Nucleus speckle Cytoplasm, cytoskeleton, cilium basal body. Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton .
Tissue Specificity
Swiss-Prot Key

 

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