Anti-CAST Antibody

Rs. 45,619.00
SKU stj115638

General Information

Product name Anti-CAST Antibody
Short Description Rabbit polyclonal to CAST
Description The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name CalpastatinCalpain inhibitorSperm BS-17 component
Immunogen A synthetic peptide corresponding to a sequence within amino acids 550-650 of human CAST (NP_001177371.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 76.6 kDa
Database Links
Alternative Names CASTCalpastatin antibodyCalpain inhibitor antibodySperm BS-17 componentCAST
Function Specific inhibition of calpain (calcium-dependent cysteine protease), Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue
Cellular Localization
Tissue Specificity
Swiss-Prot Key

 

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