Anti-CAT Antibody

Rs. 61,689.00
SKU stj27228

General Information

Product name Anti-CAT Antibody
Short Description Rabbit polyclonal to CAT
Description This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
Applications WB,IHC,FC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
FC 1:20 - 1:50
Protein Name Anti-CAT Antibody
Immunogen A synthetic peptide of human CAT
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 59.8 kDa
Database Links
Alternative Names CATCatalase CAT
Function Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide, Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Cellular Localization Peroxisome
Tissue Specificity
Swiss-Prot Key

 

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