Anti-CAV1 Antibody (Biotin)

Rs. 68,577.00
SKU stj73171

General Information

Product name Anti-CAV1 Antibody (Biotin)
Short Description Goat polyclonal to CAV1 (Biotin)
Description
Applications ELISA, WB, ICC
Dilution range
Protein Name Anti-CAV1 Antibody (Biotin)
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Biotin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 20.5 kDa
Database Links
Alternative Names CAV1Caveolin-1CAV1 antibodyCAV
Function May act as a scaffolding protein within caveolar membranes, Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity), Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation, Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner, Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway, Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation ,
Cellular Localization Golgi apparatus membrane
Tissue Specificity Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level), expressed in the brain,
Swiss-Prot Key

 

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