Anti-CAV3 Antibody

Rs. 45,619.00
SKU stj114642

General Information

Product name Anti-CAV3 Antibody
Short Description Rabbit polyclonal to CAV3
Description This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Caveolin-3M-caveolin
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CAV3 (NP_001225.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 17.3 kDa
Database Links
Alternative Names CAV3Caveolin-3 antibodyM-caveolinCAV3
Function May act as a scaffolding protein within caveolar membranes, Interacts directly with G-protein alpha subunits and can functionally regulate their activity, May also regulate voltage-gated potassium channels, Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity), Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae.
Cellular Localization Golgi apparatus membrane.
Tissue Specificity Expressed predominantly in muscle.
Swiss-Prot Key

 

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