Anti-PTRF Antibody

Rs. 61,689.00
SKU stj27803

General Information

Product name Anti-PTRF Antibody
Short Description Rabbit polyclonal to CAVIN1
Description This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.
Applications WB,IHC
Dilution range WB 1:1000 - 1:2000
IHC 1:50 - 1:100
Protein Name Anti-PTRF Antibody
Immunogen A synthetic peptide of human PTRF
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 43.5 kDa
Database Links
Alternative Names CAVIN1Caveolae-associated protein 1 antibodyCavin-1 antibodyPolymerase I and transcript release factorCAVIN1 antibodyPTRF antibodyFKSG13
Function Plays an important role in caveolae formation and organization, Essential for the formation of caveolae in all tissues.
Cellular Localization Membrane, caveola.
Tissue Specificity
Swiss-Prot Key

 

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