Anti-CBFA2T3 Antibody

Rs. 45,619.00
SKU stj116912

General Information

Product name Anti-CBFA2T3 Antibody
Short Description Rabbit polyclonal to CBFA2T3
Description This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Protein CBFA2T3MTG8-related protein 2Myeloid translocation gene on chromosome 16 proteinhMTG16Zinc finger MYND domain-containing protein 4
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 305-390 of human CBFA2T3 (NP_005178.4).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 71.2 kDa
Database Links
Alternative Names CBFA2T3Protein CBFA2T3 antibodyMTG8-related protein 2 antibodyMyeloid translocation gene on chromosome 16 protein antibodyhMTG16 antibodyZinc finger MYND domain-containing protein 4CBFA2T3 antibodyMTG16 antibodyMTGR2 antibodyZMYND4
Function Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes.
Cellular Localization Nucleus, nucleolus, Nucleus, nucleoplasm
Tissue Specificity Widely expressed with higher expression in heart, pancreas, skeletal muscle, spleen, thymus and peripheral blood leukocytes, expressed in hematopoietic cells (at protein level).
Swiss-Prot Key

 

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