Anti-CBLC Antibody

Save 6%
Rs. 34,800.00
Rs. 32,800.00
SKU stj110099

General Information

Product name Anti-CBLC Antibody
Short Description Rabbit polyclonal to CBLC
Description This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name E3 ubiquitin-protein ligase CBL-C
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 245-474 of human CBLC (NP_036248.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 52.5 kDa
Database Links
Alternative Names CBLCE3 ubiquitin-protein ligase CBL-C CBLC antibodyCBL3 antibodyRNF57
Function Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome, Functionally coupled with the E2 ubiquitin-protein ligases UB2D1, UB2D2 and UB2D3, Regulator of EGFR mediated signal transduction
Cellular Localization
Tissue Specificity Ubiquitous.
Swiss-Prot Key

 

You recently viewed

Clear recently viewed
Print Friendly and PDF