Anti-CBR1 Antibody

Rs. 45,619.00
SKU stj27399

General Information

Product name Anti-CBR1 Antibody
Short Description Rabbit polyclonal to CBR1
Description The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:10 - 1:100
Protein Name Anti-CBR1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human CBR1 (NP_001748.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 30.4 kDa
Database Links
Alternative Names CBR1Carbonyl reductase 1 CBR1 antibodyCBR antibodyCRN antibodySDR21C1
Function NADPH-dependent reductase with broad substrate specificity, Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics, Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol, Can convert prostaglandin E2 to prostaglandin F2-alpha, Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates, Catalyzes the reduction of S-nitrosoglutathione.
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

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